Mefenamic Acid

Menorrhagia, Dysmenorrhea ... show more

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

Possible

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Pharmaceutical Class

Nonsteroidal Anti-inflammatory Drug

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Controlled Drug Substance

No

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Drug Ingredient

mefenamic acid

Summary

  • Mefenamic acid is used to relieve mild to moderate pain and reduce inflammation. It's commonly prescribed for menstrual pain, which is discomfort during menstruation, and arthritis, which is joint inflammation. It can also be used for other conditions involving pain and inflammation.

  • Mefenamic acid works by blocking the production of prostaglandins, which are chemicals in the body that cause inflammation and pain. By reducing these chemicals, it helps relieve pain and swelling, making it effective for conditions like menstrual pain and arthritis.

  • The usual starting dose for adults is 500 mg, followed by 250 mg every 6 hours as needed. It's typically taken for short-term relief, not exceeding 7 days. For children, dosing is based on weight and should be determined by a doctor. Always follow your doctor's specific dosing instructions.

  • Common side effects of Mefenamic acid include stomach upset, which is discomfort in the stomach, nausea, which is the feeling of wanting to vomit, and diarrhea, which is loose or watery stools. These effects vary from person to person and are usually mild.

  • Mefenamic acid can increase the risk of serious cardiovascular events like heart attack or stroke, especially with long-term use. It may also cause gastrointestinal issues like bleeding or ulcers. It's contraindicated in people with a history of allergic reactions to NSAIDs, which are nonsteroidal anti-inflammatory drugs.

Indications and Purpose

How does Mefenamic acid work?

Mefenamic acid works by blocking the production of prostaglandins, which are chemicals in the body that cause inflammation and pain. Think of it like turning off a faucet to stop water flow. By reducing prostaglandins, Mefenamic acid helps relieve pain and reduce inflammation. This makes it effective for conditions like menstrual pain and arthritis. Always follow your doctor's instructions when using this medication to ensure safe and effective relief.

Is Mefenamic acid effective?

Mefenamic acid is effective for relieving mild to moderate pain and reducing inflammation. It's commonly used for menstrual pain, arthritis, and other conditions involving pain and inflammation. Clinical studies support its effectiveness in providing pain relief. However, individual responses can vary, and it's important to follow your doctor's instructions for the best results. If you have concerns about its effectiveness, discuss them with your healthcare provider.

What is Mefenamic acid?

Mefenamic acid is a nonsteroidal anti-inflammatory drug, or NSAID, used to relieve mild to moderate pain and reduce inflammation. It works by blocking the production of certain chemicals in the body that cause inflammation and pain. Mefenamic acid is commonly used for menstrual pain, arthritis, and other conditions involving pain and inflammation. It's usually taken for short-term relief and should be used as directed by your doctor.

Directions for Use

For how long do I take Mefenamic acid?

Mefenamic acid is usually taken for short-term relief of pain, such as menstrual cramps or mild arthritis. It's typically used for no more than 7 days unless your doctor advises otherwise. The duration of use depends on your specific condition and response to treatment. Always follow your doctor's instructions regarding how long to take Mefenamic acid to ensure safe and effective use.

How do I dispose of Mefenamic acid?

To dispose of Mefenamic acid, take it to a drug take-back program or collection site at a pharmacy or hospital. If that's not possible, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away. This helps prevent accidental ingestion or environmental harm.

How do I take Mefenamic acid?

Take Mefenamic acid as prescribed by your doctor, usually 500 mg three times a day. It's best to take it with food to reduce stomach upset. Swallow the tablets whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses. Always follow your doctor's specific instructions regarding dosage and timing.

How long does it take for Mefenamic acid to start working?

Mefenamic acid typically starts working within 30 minutes to an hour after taking it. You may begin to feel pain relief shortly after taking the medication. The full therapeutic effect can vary depending on the condition being treated and individual response. For menstrual pain, relief is often noticeable within a few hours. Always take Mefenamic acid as prescribed for the best results and consult your doctor if you have concerns about its effectiveness.

How should I store Mefenamic acid?

Store Mefenamic acid at room temperature, away from moisture and light. Keep it in its original container with the lid tightly closed. Avoid storing it in the bathroom, where humidity can affect the medication. Keep it out of reach of children and pets to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.

What is the usual dose of Mefenamic acid?

The usual starting dose of Mefenamic acid for adults is 500 mg, followed by 250 mg every 6 hours as needed. It's typically taken for short-term relief of pain, not exceeding 7 days. The maximum recommended dose is 1,000 mg per day. For children, dosing is based on weight and should be determined by a doctor. Always follow your doctor's specific dosing instructions for your health needs.

Warnings and Precautions

Can I take Mefenamic acid with other prescription drugs?

Mefenamic acid can interact with other medications, increasing the risk of side effects. It may interact with blood thinners like warfarin, increasing bleeding risk. Combining it with other NSAIDs, which are nonsteroidal anti-inflammatory drugs, can increase the risk of stomach ulcers. It may also interact with certain blood pressure medications, reducing their effectiveness. Always inform your doctor about all medications you're taking to avoid potential interactions.

Can Mefenamic acid be taken safely while breastfeeding?

Mefenamic acid is generally not recommended while breastfeeding. It can pass into breast milk and may affect the nursing infant. Although specific adverse effects on breastfed infants are not well-documented, it's best to use caution. If you need pain relief while breastfeeding, discuss safer alternatives with your doctor. They can help you choose a medication that minimizes risk to your baby.

Can Mefenamic acid be taken safely while pregnant?

Mefenamic acid is not recommended during pregnancy, especially in the third trimester. It can affect the baby's heart and blood flow and may cause complications during delivery. Limited data is available on its safety in early pregnancy, so it's best to avoid it unless your doctor advises otherwise. If you're pregnant or planning to become pregnant, talk with your doctor about safer pain relief options.

Does Mefenamic acid have adverse effects?

Adverse effects are unwanted reactions to a medication. Common adverse effects of Mefenamic acid include stomach upset, nausea, and diarrhea. Serious side effects can include gastrointestinal bleeding, kidney problems, and allergic reactions. If you notice symptoms like severe stomach pain, black stools, or difficulty breathing, seek medical attention immediately. Always inform your doctor about any new or worsening symptoms while taking Mefenamic acid.

Does Mefenamic acid have any safety warnings?

Yes, Mefenamic acid has important safety warnings. It can increase the risk of serious cardiovascular events like heart attack or stroke, especially with long-term use. It may also cause gastrointestinal issues like bleeding, ulcers, or perforation. These risks are higher in older adults. If you experience symptoms like chest pain, shortness of breath, weakness, or slurred speech, seek medical help immediately. Always use the lowest effective dose for the shortest duration possible and follow your doctor's advice.

Is it safe to drink alcohol while taking Mefenamic acid?

It's best to avoid alcohol while taking Mefenamic acid. Alcohol can increase the risk of stomach bleeding and ulcers, which are potential side effects of this medication. Drinking alcohol may also worsen side effects like dizziness or drowsiness. If you choose to drink, do so in moderation and be aware of any warning signs like stomach pain or unusual bleeding. Talk with your doctor for personalized advice.

Is it safe to exercise while taking Mefenamic acid?

Yes, you can exercise while taking Mefenamic acid, but be mindful of how your body feels. This medication can cause dizziness or stomach upset, which might affect your ability to exercise comfortably. If you experience these symptoms, consider reducing the intensity of your workout or taking breaks. Always stay hydrated and listen to your body. If you have concerns about exercising while on this medication, consult your doctor.

Is it safe to stop Mefenamic acid?

Mefenamic acid is usually taken for short-term pain relief, so stopping it is generally safe once your symptoms improve. However, if you're taking it for a specific condition, consult your doctor before stopping. Stopping suddenly may cause your pain to return. There are no withdrawal symptoms associated with stopping Mefenamic acid. Always follow your doctor's advice on how to safely discontinue the medication.

Is Mefenamic acid addictive?

Mefenamic acid is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. This medication works by reducing inflammation and pain, and it doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Mefenamic acid doesn't carry this risk.

Is Mefenamic acid safe for the elderly?

Elderly individuals are more vulnerable to the side effects of Mefenamic acid, such as gastrointestinal bleeding and kidney problems. It's important for older adults to use the lowest effective dose for the shortest duration possible. Regular monitoring by a healthcare provider is recommended to manage any potential risks. If you're an older adult taking Mefenamic acid, discuss any concerns with your doctor to ensure safe use.

What are the most common side effects of Mefenamic acid?

Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Mefenamic acid include stomach upset, nausea, and diarrhea. These effects vary from person to person. If you notice new symptoms after starting Mefenamic acid, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.

Who should avoid taking Mefenamic acid?

Mefenamic acid should not be used if you have a history of allergic reactions to it or other NSAIDs, which are nonsteroidal anti-inflammatory drugs. It's also contraindicated in people with active gastrointestinal bleeding or ulcers, severe kidney or liver disease, and certain heart conditions. Use caution if you have asthma, as it may worsen symptoms. Always consult your doctor before starting Mefenamic acid to ensure it's safe for you.